| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| DNA topoisomerase II, alpha |
DNA topoisomerase II alpha |
protein kinase C binding,
DNA topoisomerase (ATP-hydrolyzing) activity,
DNA-dependent ATPase activity,
chromatin binding,
histone deacetylase binding,
ATP binding,
ubiquitin binding,
drug binding,
protein heterodimerization activity,
protein C-terminus binding,
protein homodimerization activity,
protein binding |
DNA topoisomerase complex (ATP-hydrolyzing),
cytoplasm,
condensed chromosome,
chromosome,
nucleolus,
nucleoplasm |
positive regulation of apoptosis,
DNA ligation,
DNA replication,
chromosome condensation,
DNA repair,
embryonic cleavage,
chromosome segregation,
phosphoinositide-mediated signaling,
apoptotic chromosome condensation,
DNA topological change,
positive regulation of transcription from RNA polymerase II promoter,
positive regulation of retroviral genome replication |
| DNA topoisomerase II |
DNA topoisomerase II (EC 5.99.1.3) (from PhosphoBase) |
DNA topoisomerase (ATP-hydrolyzing) activity,
mRNA binding,
rDNA binding,
ATP binding,
satellite DNA binding,
four-way junction DNA binding,
protein binding |
synaptonemal complex,
cytoplasm,
insoluble fraction,
soluble fraction,
chromatin accessibility complex,
mitochondrion,
chromosome |
reciprocal meiotic recombination,
chromatin silencing,
chromatin remodeling at centromere,
chromatin assembly or disassembly,
meiosis,
DNA strand elongation involved in DNA replication,
regulation of mitotic recombination,
mitotic spindle organization,
DNA topological change,
mitotic chromosome condensation,
mitotic cell cycle G2/M transition decatenation checkpoint,
metaphase plate congression |
| DNA topoisomerase II, beta |
Enzyme: Topoisomerase |
protein kinase C binding,
DNA topoisomerase (ATP-hydrolyzing) activity,
chromatin binding,
histone deacetylase binding,
ATP binding,
protein heterodimerization activity,
protein C-terminus binding |
SWI/SNF-type complex,
cytosol,
chromosome,
nucleolus,
nucleoplasm |
axonogenesis,
forebrain development,
neuron migration,
DNA topological change |
